Pak1 peptide bound LC8
PDB
3dvp
X-Ray Diffraction
Homo Sapiens
Title
Biochemical and structural characterization of the Pak1-LC8 interaction.
Date
Jan. 1, 2021
Authors
Lightcap, C.M. Sun, S. Lear, J.D. Rodeck, U. Polenova, T. Williams, J.C.
Disordered part
Chain
C
UniProt Serine/threonine-protein kinase PAK 1 (Q13153)
Region 213 - 221
In contact
Chain A
UniProt Dynein light chain 1, cytoplasmic (Q24117)
Region 5 - 89
Interacting domain
Type Identifier Name Start End
Gene3D G3DSA:3.30.740.10 Protein Inhibitor Of Neuronal Nitric Oxide Synthase; 1 89
Pfam PF01221 Dynein light chain type 1 5 88
Shared GO terms
cellular_component GO:0005634 nucleus
cellular_component GO:0005737 cytoplasm
molecular_function GO:0005515 protein binding
Chain B
UniProt Dynein light chain 1, cytoplasmic (Q24117)
Region 5 - 89
Interacting domain
Type Identifier Name Start End
Gene3D G3DSA:3.30.740.10 Protein Inhibitor Of Neuronal Nitric Oxide Synthase; 1 89
Pfam PF01221 Dynein light chain type 1 5 88
Shared GO terms
cellular_component GO:0005634 nucleus
cellular_component GO:0005737 cytoplasm
molecular_function GO:0005515 protein binding
Cross references
DisProt
ID Namespace IDPO
DP03433 Disorder function flexible linker/spacer
DP03433 Structural state disorder
Related structures
PDB Chain Start End Description
3dvp C 213 221 Pak1 peptide bound LC8
3dvp D 213 221 Pak1 peptide bound LC8
1zsg B 183 204 beta PIX-SH3 complexed with an atypical peptide from alpha-PAK